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Friday, June 05, 2020 10:03:39 AM
6/5/20, 6:54 AM
“Sorrento Therapeutics Inc. shares rose 10% to $4.26 after the company said it has completed a preclinical batch of the STI-4398 protein and is reporting positive results from preclinical testing of its ability to neutralize and inhibit SARS-CoV-2 virus from infecting ACE2-expressing cells, VERO/E6.
The biopharmaceutical company said STI-1499 could be a antidote for Covid-19 pending successful demonstration of its safety and efficacy in pre-clinical and clinical studies.
Sorrento said March 20 that it had designed and produced its STI-4398 product candidate as a binding protein to the spike protein of the SARS-Cov-2 virus.
Sorrento said it has discussed with the Food and Drug Administration the development of this drug candidate and has received guidance on the path forward to a clinical trial for STI-4398 for both the potential treatment of infected patients and as a potential prophylactic treatment to Covid-19.
Write to Chris Wack at chris.wack@wsj.com”
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