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Re: JustAguy22 post# 82240

Wednesday, 06/03/2020 5:29:14 PM

Wednesday, June 03, 2020 5:29:14 PM

Post# of 232933
Thanks for asking. I must not have been clear.

The technical issue is whether we need a one-sided (leron better than placebo) or two sided (leron not equal to placebo) confidence interval. A 95% interval (p<.05) one-sided is a 90% interval (p<.1) two sided. The latter makes sense with a drug that might do damage.

So, given 17 placebo and 34 leronlimab patients, my table could read

___________Maximum Leronlimab deaths for significance (p<.05):

If Placebo____One-sided test_____Two sided
deaths are

10 (59%)__________12 (35%)____________11
12 (71%)__________15 (44%)____________14

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