Cytodyn Inc (CYDY)

[Borel Fields]

Just ran some confidence intervals using Wolfram Alpha assuming 34 leron patients / 17 placebo in the severe/critical trial.

(jargon: read P(die|leron) as "probability of death given received leronlimab")

I assume one-sided 95% intervals, that is, testing whether P(die|leron) < P(die|placebo). Some would argue two-sided - that's not appropriate given leron's safety profile. Results:

If observed P(die|placebo) = .71 (12/17)
result is significant if observed P(die|leron) =< .44 (15/34)

If observed P(die|placebo) = .59 (10/17)
result is significant if observed P(die|leron) =< .35 (12/34)

In each case, the two-sided interval would require leron to save one additional person.