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Genetic Engineering & Biotechnology News: (article in GEN)

p53’s Multiple Roles Are Acquired during Pluripotent Stem Cell Differentiation

The p53 gene is extremely important in cell biology as its role is to regulate the cell cycle and halt the formation of tumors, leading to its nickname the “tumor suppressor gene.” However, previous efforts to determine whether p53 is behind apoptosis induced by DNA damage in pluripotent embryonic stem cells (ESCs) produced conflicting results. NIH researchers say their report sorts through this maze of contradictions to finally determine that the multiple roles of p53 in cell cycle regulation and apoptosis are acquired during pluripotent stem cell differentiation. + MORE

As Dr Fauci might say "many shots on goal"..

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