CV Sciences Inc (CVSI)

[Deetew]

Comment: It is not obvious why an ACE2 inhibitor would be helpful to someone with COVID-19. According to other articles, COVID attacks ACE2, leading to hypertension and lung failure. Other proposed therapies increase, not decrease, the levels of ACE2 in the lungs.

Also, what is a “strain” of CBD? Isn’t one CBD molecule the same as the next???

Response 1 to Comment 11
Received: 25 May 2020
Commenter: Igor Kovalchuk

The commenter has declared there is no conflict of interests.

Comment: Thanks for your comment. We never stated it is ACE2 inhibitor. Our data show that ACE2 expression (number of receptors per cell) decrease - it does not mean that ACE2 is inhibited - there are just fewer number of molecules per cell after the treatment with extracts, And it is not a "strain" of CBD, but extracts high in CBD, meaning that CBD is a dominant molecule in the extract. Hope this helps. Igor

https://www.preprints.org/manuscript/202004.0315/v1