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Re: Jimmy Joe post# 12065

Wednesday, 05/27/2020 5:56:01 PM

Wednesday, May 27, 2020 5:56:01 PM

Post# of 14686

Why all the misinformation from this broker? This is not a cannabis play






I have no idea if Generex is now or ever was truly developing any cannabis products. They have a habit of chasing shiny objects and signing letters of intent. Whether they were or were not, they certainly SAID they were. Starting in 2015, Generex started hyping cannabis just like every other penny stock. I've never seen any public statements from Joe disavowing all their previous PR's on the subject. If somebody wants to ask why some European brokerage just now decided to stick it to them five years after the fact, then that is a reasonable question. But it strains credulity for them or anyone to try to say now that they weren't at least pretending to be a cannabis player 2015-2019. My suspicion is RapidMist cannabis project is long dead for multiple reasons. I have the endorsement on my medical license that allows me to prescribe medical marijuana, and I can tell you not one patient has ever said to me that what the dispensaries really need is some remarkably-average Canadian weed in a really expensive dispenser that works kinda okay. The oral tinctures work great for buccal absorption without the RapidMist inhaler. Plus, we understand THC metabolism a lot better than we did in 2015. Buccal absorption was considered very promising because it avoids the "first pass metabolism" through the liver, which degrades the THC by 70-80% before it is distributed to the brain. This can be measured, and THC degradation pharmacokinetic curves can be drawn which will make a stoner cry. BUT! Stoners, chill! Science to the rescue. We understand now that some of the metabolite products from THC's first pass metabolism are just as psychoactive as THC. There are more of them, and they cross the blood-brain barrier more readily than the Momma THC molecule. So it may take longer to get high, but there is usually an enhanced and prolonged psychoactive effect from oral absorption compared with buccal absorption. Long story short, buccal absorption of THC is not as big a deal as we thought it would be, and even if it was, tinctures work just fine without RapidMist technology. I never paid any attention to CBD soft drink nonsense, so I have no idea what they're up to with that, but Generex most definitely did claim to be a cannabis play, in multiple ways, and has never said otherwise. I'm sorry that is causing problems now, but denying reality has not been working out well lately, so let's confront the truth for a change.




https://www.prnewswire.com/news-releases/generex-announces-issuance-of-buccal-cannabis-white-paper-300152469.html

Generex Announces Issuance of Buccal Cannabis White Paper
NEWS PROVIDED BY

Generex Biotechnology Corporation
Oct 01, 2015, 09:30 ET

WORCESTER, Mass. and TORONTO, Oct. 1, 2015 /PRNewswire/ -- Generex Biotechnology Corporation (www.generex.com) (OTCQB: GNBT) today announced the issuance of a white paper on the use of cannabis for medicinal purposes and the joint venture between Generex and CannScience Innovations Inc. (www.cannsci.com) for the design and development of products for the delivery of cannabinoids and cannabinoid-derived formulations into the human body via the buccal mucosa (the inner lining of the mouth).

The white paper is authored by Dr. Lakshmi P. Kotra, B. Pharm. (Hons), Ph.D. and Dr. Angelica M. Bello. Dr. Kotra is the Director at the Center for Molecular Design and Preformulations (CMDP) at University Health Network (UHN) in Toronto, Canada, a scientist and principal investigator at UHN, and an Associate Professor of Medicinal Chemistry at the Leslie Dan Faculty of Pharmacy, University of Toronto (www.uhnresearch.ca/kotralab). Dr. Bello is a scientific associate at UHN.

The white paper may be viewed online on the Generex website.






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