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Tuesday, 05/26/2020 5:20:15 PM

Tuesday, May 26, 2020 5:20:15 PM

Post# of 251715
BMY inks oncology-drug-discovery collaboration with—(private)—Repare Therapeutics:

https://www.businesswire.com/news/home/20200526005805/en/Repare-Therapeutics-Announces-Multi-Target-Discovery-Collaboration-Bristol

Repare Therapeutics Inc., a precision oncology company pioneering synthetic lethality to develop novel therapeutics that target specific vulnerabilities of tumors in genetically defined patient populations, today announced it has entered into an exclusive, worldwide research collaboration with Bristol Myers Squibb.

…Under the terms of the agreement, the companies will leverage Repare’s proprietary, CRISPR-enabled genome-wide synthetic lethal target discovery platform, SNIPRx, to jointly identify multiple synthetic lethal precision oncology targets for drug candidates. Repare will grant BMS exclusive worldwide rights to develop and commercialize therapeutics for select validated synthetic lethal precision oncology targets discovered under the collaboration.

As part of the agreement, BMS will make an upfront payment of $65 million which includes a $15 million equity investment in Repare. Repare will be eligible to receive up to approximately $3 billion in license fees, discovery, development, regulatory and sales-based milestones, in addition to royalty payments on net sales of each product commercialized by BMS.


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