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Re: Pipilongstocking post# 296931

Friday, 05/15/2020 10:33:00 AM

Friday, May 15, 2020 10:33:00 AM

Post# of 402741
Interesting results where hydroxychloroquine was statistically indistinguishable from standard of care patients. That is other than 10% of hydroxychloroquine patients had to discontinue, a finding that confirmed several other studies.

“ Results In the main analysis, 84 patients who received hydroxychloroquine within 48 hours of admission to hospital (treatment group) were compared with 89 patients who did not receive hydroxychloroquine (control group). Eight additional patients received hydroxychloroquine more than 48 hours after admission. In the weighted analyses, the survival rate without transfer to the intensive care unit at day 21 was 76% in the treatment group and 75% in the control group (weighted hazard ratio 0.9, 95% confidence interval 0.4 to 2.1). Overall survival at day 21 was 89% in the treatment group and 91% in the control group (1.2, 0.4 to 3.3). Survival without acute respiratory distress syndrome at day 21 was 69% in the treatment group compared with 74% in the control group (1.3, 0.7 to 2.6). At day 21, 82% of patients in the treatment group had been weaned from oxygen compared with 76% in the control group (weighted risk ratio 1.1, 95% confidence interval 0.9 to 1.3). Eight patients in the treatment group (10%) experienced electrocardiographic modifications that required discontinuation of treatment.”
https://www.bmj.com/content/369/bmj.m1844

Thanks pipilongstocking!

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