Friday, May 08, 2020 3:24:18 PM
I wish we had some knowledge of just how much PLX-PAD is already in cryogenic storage worldwide. I was once of the belief that it was substantial, but don't know that's true. At 20,000 doses from a single placenta, it doesn't sound like all that many placenta's would be needed to cover all on ventilators, currently under 20K for the U.S. but the source doesn't account for patients coming off, and others going on. Here's a link at where I found it.
https://covid19.healthdata.org/united-states-of-america
No doubt, the number worldwide would be a good size multiple, but if a single vial will do a patient, it would seem like the output from under a dozen placenta's could provide the needed doses. I believe the bigger number would be if the drug were given prior to going on ventilator, to hopefully prevent the need for a ventilator at all, and probably prevent a lot of organ damage. Clearly that number would be higher, but once pneumonia was seen, it might greatly reduce hospitalization if it could be given at that point. Far more drug would be needed, but overall healthcare costs should drop dramatically as many could completely avoid hospitalization completely.
Gary
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