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Re: knuts4oe post# 30291

Thursday, 04/30/2020 6:02:42 PM

Thursday, April 30, 2020 6:02:42 PM

Post# of 30990
MYMD PHARMA PART 2 "About Us"
"Work performed at the Johns Hopkins School of Medicine, recently published in The Journal of Immunology, has shown that MYMD-1 specifically targets subsets of T lymphocytes called effector T cells by reducing their activity. Effector T cells are involved in mediating a broad spectrum of autoimmune diseases. The studies further showed that MYMD-1 has a broad spectrum effect on the immunometabolic system including, suppressing in vitro the production of the pro-inflammatory cytokine TNF-alpha by effector T helper 1 T lymphocytes (Th1 cells), reducing nitrite and increasing hydrogen sulfide. Multiple mouse disease models have demonstrated that MYMD-1 decreased the incidence and severity of MS, and significantly extended longevity and reversed signs of aging."

"MYMD-1 is a small molecule with a benign safety profile as demonstrated in pre-clinical studies. Phase 1 human safety and dosing trials are scheduled for completion in 2019"

"As an immunometabolic regulator, MYMD-1 uniquely targets the rate of cellular oxidation as the underlying cause (as opposed to the symptom) of many currently uncured diseases. Accordingly, the therapeutic scope of our lead candidate is being expanded through ongoing preclinical studies focused on additional age-related diseases, virtually all autoimmune diseases, Alzheimer's disease, various cancers and heart disease."

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