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Northwestern testing drug to help treat a ‘storm’ inside the body caused by COVID-19

Chicago Tribune |
Apr 24, 2020 | 6:15 PM

Some patients with the novel coronavirus suffer a severe immune response that triggers potentially fatal hyperinflammation, studies have shown. The reaction, named for the body’s proteins that attack lung tissue, is known as a “cytokine storm.”

Northwestern Medicine in Chicago is testing a drug called sarilumab, which is otherwise used to reduce inflammation in rheumatoid arthritis.

“We have no therapy for COVID-19, per se,” Wunderink explained. “We are managing these patients using what research has shown is the best management for acute respiratory distress syndrome, so that’s the best we have to offer.”

The research is part of a global clinical trial of more than 1,000 patients sponsored by the drug’s maker, Regeneron Pharmaceuticals.

https://www.chicagotribune.com/coronavirus/ct-coronavirus-illinois-northwestern-sarilumab-trial-20200424-52hatrmw7vaqtd6ohahx5bsthq-story.html