Seems like lots of groups are targeting Aurora kinase. Off the top of my head there is Merck/Vertex, MLNM, RIGL, AZN (?), and I rememeber that IMCL had a paper with early stage research on Aurora kinase inhibitors (from Imclone's small molecule division-now closed down). From the papers that I have seen there is a debate about how to best target Aurora kinase--> target the A or B isoform or target both.
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