Kraig Biocraft Laboratories Inc (KBLB)

[GTman1]

a lot of proteins could be produced in it if not for the silk fixation of the company. To produce a protein and let it accumulate in the fat body

Wait, what? You do realize a fat cell is a "cell", right? Not a protein. And not a gland either, like a silk gland, that can efficiently produce large amounts of protein (and more importantly, one targeted type of protein if desired).

The main function of the fat cell is to store triglycerides (lots of them, and they are not proteins) for the silkworm (in this case) to use as energy at a later time. Expressing any amount of a foreign protein within a fat cell could have huge implications on the silkworms metabolism and access to energy, not to mention neural/motor functions and normal functions within the cell. Fat cells already produce small amounts of thousands of different proteins that facilitate the cells normal function, so how much room is there to add usable amounts of silk protein? It would be such a negligible amount of your target protein that you might as well use an existing platform. Just because you think 50% of a silkworms body mass is fat, doesn't mean even a tiny bit of that wt/wt can be converted to usable proteins.

as I originally suggested is not hard at all

Thats like saying:

Step #1: Steal underpants
Step #2: ?
Step #3: Profits!

If you know of a way to express usable amounts of non-native protein (better than yeast or bacteria) within a fat cell, please enlighten us. I certainly have never heard of it. *I'll brace for the fringe article*