"INVESTMENTS, RETURNS": The cost of the GVP represents a sizable investment and, even if a large number of potential zoonoses are discovered, only a minority is likely to have the potential to cause large-scale outbreaks and mortality in people. However, given the high cost of single epidemic events, data produced by the GVP may provide substantial return on investment by enhancing diagnostic capacity in the early stages of a new disease outbreak or by rapidly identifying spillover hosts, for example. Recent analysis of the exponentially rising economic damages from increasing rates of zoonotic disease emergence suggests that strategies to mitigate pandemics would provide a 10:1 return on investment . Even small reductions in the estimated costs of a future influenza pandemic (hundreds of billions of dollars) or of the previous SARS (severe acute respiratory syndrome) epidemic ($10 billion to $30 billion) could be substantial. http://www.caspmi.cn/gaog/pdf/2018/4.pdf