Thursday, April 02, 2020 5:09:57 PM
1. A composition comprising a therapeutically effective amount of undifferentiated placenta-derived three-dimensional (3D)-expanded, adherent stromal cells in a liquid suspension, wherein the adherent stromal cells do not express CD34, in the preparation of a medicament for treating an autoimmune disease, wherein the composition is indicated for systemic administration.
2. The composition of claim 1, wherein at least 10% of said cells are at a proliferative phase.
3. The composition of claim 1, wherein the autoimmune disease is an autoimmune cardiovascular disease.
4. The composition of claim 1, wherein the autoimmune disease is an autoimmune rheumatoid disease.
5. The composition of claim 1, wherein the autoimmune disease is an autoimmune glandular disease.
6. The composition of claim 1, wherein the autoimmune disease is an autoimmune gastrointestinal disease.
7. The composition of claim 1, wherein the autoimmune disease is an autoimmune cutaneous disease.
8. The composition of claim 1, wherein the autoimmune disease is an autoimmune hepatic disease.
9. The composition of claim 1, wherein the autoimmune disease is an autoimmune neurological disease.
10. The composition of claim 1, wherein the autoimmune disease is an autoimmune muscular disease.
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11. The composition of claim 1, wherein the autoimmune disease is an autoimmune nephric disease.
12. The composition of claim 1, wherein the autoimmune disease is an autoimmune connective tissue disease.
13. The composition of claim 1, wherein the autoimmune disease is an autoimmune systemic disease.
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