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Re: swampboots post# 229951

Saturday, 03/28/2020 11:26:58 PM

Saturday, March 28, 2020 11:26:58 PM

Post# of 252255
looks like you were given the dangerously dumbed down version. Bottom line is that whatever breaks down or alters the virus structure, destroys it. Heat doesn’t melt the lipid layer; it can cause a variety of disruptions but melting isn’t one of them. Likewise, various solvents don’t dissolve the lipid or proteins - at least while the virus is intact. If broken down stuff dissolves, that matters less than the breaking up. Some of the solvents u mentioned change the chemistry of the virus in such a way that it may lose structural integrity. I’d bet that 40% alcohol would deactivate the virus but it might take longer than 80% alcohol. Folks tend to conflate variable effects. I suspect the alcohol changes the water activity outside the range at which the virus is stable. If that’s true, then anything that can cause that change in water activity could deactivate the virus, eg a sufficiently concentrated salt solution might do the trick (don’t take that as fact). Lastly, the virus is not 1 protein but several and they serve different purposes and some are combined to form larger structures. Break up or change any part of that, then the job is done. I don’t know where vinmantoo got his 55 degC number. I suspect it corresponds to the highest temperature at which organisms have been observed. Creatures don’t tend to exist at higher temps because the protein structures degrade. A virus isn’t an organism and I don’t know if viral proteins are generally more or less temperature sensitive. Lower temperatures might do the trick but I doubt there are any data specific to CV19. other environmental variables can affect the temp at which proteins unfold or the lipid layer breaks down. 25 degC is probably too low w/o other, more important, contributing factors. I suspect the porous materials stuff is bunk. Some viruses survive quite nicely in the porous material some folks call rock and sediment. I don’t know if CV19 can and I doubt anyone else can say w certainty.

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