Innovation Pharmaceuticals Inc (IPIX)

[Jhawker]

Here is the problem with the malaria drug.
“ But chloroquine still has the same Wuhan issue illustrated by its previous use for malaria–evolving resistance. RNA viruses like Wuhan coronavirus mutate rapidly (explained in my first post on this topic). The most conserved protein is necessarily the RNA polymerase. We know this from influenza, where it is the hemagglutinin and neuraminidase envelope proteins (equivalent to Wuhan S) that mutate so the annual vaccine is never ‘right’. Chloroquine may well be effective now, but if Wuhan coronavirus becomes endemic (now likely given its spread in Africa and Southeast Asia), then it is not a long-term solution like a vaccine. But it will probably buy the precious time to get a vaccine.”
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