Algernon Pharmaceuticals Inc (AGNPF)

[medchem]

Front page of CNN: Ifenprodil identified by super computer as a drug (among others) that might decrease infectivity of coronavirus:

You can download the results for free I put the link below. This was highlighted in CNN yesterday, front page!

If you want me to explain these findings further just let me know.

Our boys at Algernon may have found a miracle drug.

Some science:

A recent publication from Oakridge National Laboratory (USA Department of Energy), "Repurposing Therapeutics for COVID-19: Supercomputer-Based Docking to the SARS-CoV-2 Viral Spike Protein and Viral Spike Protein-Human ACE2 Interface". The authors performed computational modelling utilizing SUMMIT (the worlds fastest super computing system) and screened libraries of existing drugs to check for interaction between spike protein (Sars-Cov-2) and human ACE2 receptor which revealed that Ifenprodil may play a role in diminishing coronavirus infectivity.


As described in their abstract,

Quote:They sought to identify small-molecules which bind to either the isolated Viral S-protein at its host receptor region or to the S protein-human ACE2 interface. They hypothesized the identified small-molecules may be repurposed to limit viral recognition of host cells and/or disrupt host-virus interactions.



They provided a ranked list of compounds that could be tested experimentally. Ifenprodil is on the list (go to the link below and download the supplementary information excel files... it's listed in both).

Download the files here

https://www.cnn.com/2020/03/19/us/fastest-supercomputer-coronavirus-scn-trnd/index.html

or i can directly email you the files, just send me you email by PM