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Re: edwardport post# 59803

Friday, 03/20/2020 4:48:11 AM

Friday, March 20, 2020 4:48:11 AM

Post# of 232975

A recent well controlled clinical study conducted by Didier Raoult? M.D/Ph.D, et. al in France has shown that 100% of patients that received a combination of HCQ and Azithromycin tested negative and were virologically cured within 6 days of treatment.


Good results so far, still room for leronlimab as treatment with those who were dropped from the trial. With only six patients on HCQ + Azithromycin the study needs to be expanded. HCQ may also not be the best treatment for everyone.

Moreover, chloroquine is not listed among the four treatments studied as part of the recently launched European clinical trial piloted by Inserm, which includes 3200 severe hospitalised patients, including 800 French patients.

Chloroquine was ruled out due to the risk of interactions with other medications for common comorbidities in infected patients, and because of possible adverse effects in patients undergoing resuscitation.


https://www.medscape.com/viewarticle/927033

Trial included 36 adult patients, 26 received HCQ & 16 controls. Six out of 42 patients meeting inclusion criteria lost to follow up. (All from treatment group: 3 transferred to ICU, 1 death, 1 left hospital, 1 stopped HCQ bc nausea. No control patients lost to follow-up.)

HCQ-treated patients average age 51.2 yrs vs control patients average age of 37.3 yrs. Six patients receiving HCQ received azithromycin on day 1 (unclear how certain patients were selected to receive azithromycin).

Results on Day 6:
-12.5% of control patients virologically cured
-57.1% of HCQ treated patients virologically cured
-100% of HCQ + Azithromycin patients virologically cured


https://threadreaderapp.com/thread/1240314674358505473.html
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