This is going down over the next 3 days and I don't mean GOVX
Featured presenter for upcoming meeting
Chief Scientific Officer, Farshad Guirakhoo, PhD, will be a featured speaker at the World Immunotherapy Congress, being held March 2-4, 2020 in San Diego, California.
Dr. Guirakhoo also expects to give a current update on the Company’s collaboration with BravoVax, based in Wuhan, China, on use of GeoVax’s vaccine technology platform and expertise to develop a vaccine for prevention/control of the novel coronavirus disease (COVID-19).
SURGE
GeoVax Labs, Inc. (OTC: GOVX), a biotechnology company developing human immunotherapies and vaccines against infectious diseases and cancer, announced today that its Chief Scientific Officer, Farshad Guirakhoo, PhD, will be a featured speaker at the World Immunotherapy Congress, being held March 2-4, 2020 in San Diego, California.
Dr. Guirakhoo will deliver two presentations during the conference. The first, on March 2, is entitled Utilizing a Live Modified Vaccinia Ankara Virus to Deliver Tumor Associated Antigen MUC1 on the Surface of Virus Like Particles and will focus on GeoVax’s efforts toward development of cancer immunotherapies.
During his second presentation on March 4, entitled Development of Single Dose Vaccines for Emerging Infectious Diseases Using a Novel MVA Platform, Dr. Guirakhoo will discuss the Company’s design of MVA-VLP and non-VLP vaccines for Zika, Ebola, Marburg and Lassa fever vaccines, as well as results from efficacy studies in animal challenge models.During this presentation, Dr. Guirakhoo also expects to give a current update on the Company’s collaboration with BravoVax, based in Wuhan, China, on use of GeoVax’s vaccine technology platform and expertise to develop a vaccine for prevention/control of the novel coronavirus disease (COVID-19).
GeoVax’s Modified Vaccinia Ankara Virus Like Particles (GV-MVA-VLPTM) platform technology is built on a proprietary MVA vector system that is optimized for high expression and stable transgenes during manufacture. Similar to its parent MVA, it has the advantages of being a live replication-competent vector in avian cells for manufacturing, yet replication-deficient in mammalian cells for vaccination, thus inherently safe. Importantly, GV-MVA-VLPTMvaccines elicit protective T cell as well as antibody responses (Th1 biased) in animals and humans. In non-clinical studies, GV-MVA-VLPTM vaccine candidates against various virus families (e.g. Ebola, Marburg, Lassa and Zika) induced strong antibody and T cell responses and conferred full protection after single dose vaccinations against lethal challenges. Single dose protection is a favourable characteristic of preventive vaccines for emerging infectious disease outbreak response, given the speed of spread of pathogens and the impracticality of multi-dose regimens in the under-resourced settings where outbreaks often occur.
Built upon the GV-MVA-VLPTM platform, GeoVax’s preventive HIV vaccine (GOVX-B11) has demonstrated robust and durable immune responses in clinical trials involving more than 500 subjects and the therapeutic version of the vaccine (GOVX-B01) is currently planned to be evaluated as a component in two independent phase 1 studies aimed at developing a “functional cure” for HIV infected individuals. Similar to the HIV therapeutic approach where a combination of drugs and vaccine platforms will be required to potentially cure chronically infected individuals, GeoVax expects its cancer vaccines will also be used in combination with peptide vaccines and checkpoint inhibitors which have already shown some positive effects in clinical studies.
