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Wednesday, February 12, 2020 7:52:44 AM
Definitely a positive step in that provisional TradeMark.
Count me in on this at $1.32 this AM
It should see $2 easy on this.
And make up for that loss on MYO you had the other day
GO $AIM
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Press Release: AIM ImmunoTech Files Three Provisional Patent Applications Surrounding Ampligen(R) for Use Against the SARS-like Wuhan 2019 Novel Coronavirus
6:30 AM ET 2/11/20 | Dow Jones
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Real time quote.
Ampligen(R) obtained 100% survival rate at clinically achievable human
dosage levels for SARS in animal experiments
Ampligen key to proposed broad-spectrum 'universal' coronavirus vaccine
OCALA, Fla., Feb. 11, 2020 (GLOBE NEWSWIRE) -- AIM ImmunoTech Inc. (NYSE
American: AIM) today announced the filing of three provisional patent
applications related to its drug candidate Ampligen in the company's
efforts toward joining the global health community in the fight against
the deadly Wuhan coronavirus that has so far infected approximately
40,000 people and killed almost one thousand, primarily in China.
Coronaviruses are a large family of viruses, including the deadly Severe
Acute Respiratory Syndrome (SARS). After a 2002 SARS outbreak in the
Guangdong province of southern China caused more than 8,000 cases and
more than 800 deaths, the United States' National Institutes of Health
contracted studies to evaluate potential treatments for SARS. Ampligen
achieved a 100% survival rate -- as compared to 100% mortality -- at
clinically achievable human dosage levels in animal experiments. The
SARS virus is very similar in key RNA sequences to the Wuhan coronavirus,
and the company expects Ampligen to be similarly effective with the
Wuhan coronavirus.
AIM -- which is an immuno-pharma company focused on the research and
development of therapeutics to treat immune disorders, viral diseases
and multiple types of cancers -- is already focused on avenues to
provide the company's Ampligen technology to the countries primarily
afflicted by the pandemic.
AIM believes that Ampligen has the potential to be both an early-onset
treatment for and prophylaxis against the Wuhan coronavirus, which
originated in China before quickly spreading to other countries. The
company's three provisional patent applications include: 1) Ampligen as
a therapy for the Wuhan coronavirus; 2) Ampligen as part of a proposed
intranasal universal coronavirus vaccine that combines Ampligen with
inactivated Wuhan coronavirus, conveying immunity and cross-protection
and; 3) a high-volume manufacturing process for Ampligen. Under the
Patent Cooperation Treaty of 1970, which provides international
protections for patents, the three provisional patent applications can
convert to international patent applications based on the date of their
filings. Alternatively, direct national filings in many countries are
possible under the Paris Convention for the Protection of Industrial
Property of 1883 -- an international agreement. China, the epicenter of
the epidemic, is a signatory of both the treaty and the agreement.
"Our analysis of the RNA sequences of the SARS virus and the Wuhan
coronavirus and our research lead AIM to believe Ampligen has
significant therapeutic potential as both an early-onset treatment and
prophylaxis against this new and deadly virus," said AIM CEO Thomas K.
Equels. "If clinical trials follow the results of SARS animal testing,
this means helping people who are already sick as well as a prophylaxis
for people directly exposed to the virus as it spreads, which is
especially important for the medical professionals in hospital-like
settings working to contain the global emergency, and those people
quarantined in camps and on cruise ships. AIM's universal coronavirus
vaccine concept is primarily meant to inoculate against the Wuhan
coronavirus, but, through Ampligen's unique capabilities, could also
protect against other forms of coronavirus and future mutations of the
Wuhan coronavirus. AIM is a small immunological research company, but we
want to do our part. We believe humanity must stand together to defeat
such viral threats. This is our effort to make a difference in this
worldwide threat posed by the Wuhan coronavirus."
Ampligen is the only known specific Toll-Like Receptor 3 agonist based
on synthetic double-stranded RNA with a well-developed intravenous,
intraperitoneal and intranasal safety profile while demonstrating strong
antiviral activity against a broad spectrum of viruses. The drug is also
being used in multiple ongoing immuno-oncology clinical studies. AIM has
recently produced more than 10,000 vials of Ampligen.
About AIM ImmunoTech Inc.
AIM ImmunoTech Inc. is an immuno-pharma company focused on the research
and development of therapeutics to treat immune disorders, viral
diseases and multiple types of cancers. AIM's flagship products include
the Argentina-approved drug rintatolimod (trade names Ampligen(R) or
Rintamod(R) ) and the FDA-approved drug Alferon N Injection(R) . Based
on results of published, peer-reviewed pre-clinical studies and clinical
trials, AIM believes that Ampligen(R) may have broad-spectrum anti-viral
and anti-cancer properties. Clinical trials of Ampligen(R) include
studies of cancer patients with renal cell carcinoma, malignant melanoma,
colorectal cancer, advanced recurrent ovarian cancer and triple negative
metastatic breast cancer. These and other potential uses will require
additional clinical trials to confirm the safety and effectiveness data
necessary to support regulatory approval and additional funding.
Rintatolimod is a double-stranded RNA being developed for globally
important debilitating diseases and disorders of the immune system.
Cautionary Statement
Some of the statements included in this press release may be
forward-looking statements that involve a number of risks and
uncertainties. For example, the filing of provisional patent
applications provides no assurance that patents will ultimately be
granted. No assurance can be made as to any future clinical trials
related to the matter herein. No assurance can be given as to whether
the current or planned trials will be successful or yield favorable data
and the trials are subject to many factors including lack of regulatory
approval(s), lack of study drug, or a change in priorities at the
institutions sponsoring other trials. In addition, initiation of planned
clinical trials may not occur secondary to many factors including lack
of regulatory approval(s) or lack of study drug. Even if these clinical
trials are initiated, we cannot assure that the clinical studies will be
successful or yield any useful data or require additional funding. Among
other things, for forward-looking statements, we claim the protection of
the safe harbor for forward-looking statements contained in the Private
Securities Litigation Reform Act of 1995. Any forward-looking statements
set forth in this press release speak only as of the date of this press
release. We do not undertake to update any of these forward-looking
statements to reflect events or circumstances that occur after the date
hereof. This press release and prior releases are available at
www.aimimmuno.com. The information found on our website is not
incorporated by reference into this press release and is included for
reference purposes only.
Contacts:
Crescendo Communications, LLC
Phone: 212-671-1021
Email:
https://www.globenewswire.com/Tracker?data=Tp9mWy9cd-m9T0c218xDP0hiA9tB9FHT5OZjhHYKwy9jwLJYiwVojT2jTg7KeNBSq9BnnnxQIOM89SnL3hFfcK9d283UKTT2NrFLaTFozzk=
aim@crescendo-ir.com
AIM ImmunoTech Inc.
Phone: 800-778-4042
Email:
https://www.globenewswire.com/Tracker?data=nBBsoDQ9bbvt5wddaVT2IvDn0nIj9-vCI76FRWrqeqVmTxDExd4Q2smKWjb61_FtoSRv55bNEzHrSmjUcVbpvQ==
IR@aimimmuno.com
A photo accompanying this announcement is available at
https://www.globenewswire.com/NewsRoom/AttachmentNg/d12855ed-8007-4ebe-bef5-6b3aaac80729.
> Dow Jones Newswires
February 11, 2020 06:30 ET (11:30 GMT)
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