Arrayit Corporation (ARYC)

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Published online 2019 Nov 20. doi: 10.1177/1179173X19885397
PMCID: PMC6868578
PMID: 31798305
Electronic Nicotine Delivery Systems and Serum Folate: A Case Study


Dried blood spots
Dried blood spots were collected on Arrayit blood cards, which use linear flow chromatography to separate whole blood serum from erythrocytes and leukocytes. A total of 5 Arrayit cards were collected from the participant: 1 at baseline and weekly thereafter over an approximate 28-day observation period. Erythrocyte folate values were assayed only at baseline as the values are a moving average of past 120-day consumption and absorption. They are not expected to vary greatly over a 28-day period. Serum folate values were assayed for each sample, as serum folate includes past 24-hour consumption and absorption. Lactobacillus casei microbiological assay of folic acid derivatives was completed with microtiter plates.