From the yahoo board
SilverFox10 hours ago
FYI: Potential drug Pfizer utilizing Antares Rescue Pen
I came across a ‘potential’ combination drug device rescue pen that Pfizer may be working on in which they have agreed to partner with ATRS per press release dated back on August 6, 2018. Pfizer has not announced it’s developmental drug at this time but a drug being developed by Zealand's Pharma in which it is developing a rescue pen for hypoglycemia and is currently in Phase 3 trials would qualify as a candidate. Zealand’s drug is “Dasiglucagon” and is being developed to offer a stable ready-to-use rescue treatment for severe hypoglycemia.
All type 1 diabetes patients and the most severely affected type 2 patients depend on insulin injections to maintain blood glucose. Consequently, patients must monitor and adjust their blood glucose levels to remain in proper glycemic control, as both high and low blood glucose may affect their health, both in the short and long term.
Severe hypoglycemia is an acute, life-threatening condition resulting from a critical drop in blood glucose levels associated primarily with insulin therapy and is one of the most feared complications of diabetes treatment. The condition of severe hypoglycemia is most frequently seen in people who inject insulin multiple times per day.
Insulin-dependent diabetics, both type 1 and type 2, can have episodes of severe hypoglycemia, resulting in confusion, loss of consciousness and even death.
With six (6) million or more people across the U.S. using insulin, there's a major need for a treatment for hypoglycemia.
While mild hypoglycemia can be treated by eating or drinking something high in carbohydrates, severe acute episodes require intravenous glucose or an injection of glucagon. Glucagon powder, such as in the GlucaGen HypoKit, requires reconstitution and injection with a syringe. Zealand's approach is a ready-to-use "rescue pen" known as HypoPal.
How common is Diabetes?:
Type 2 diabetes is much more common that type 1. According to the 2017 National Diabetes Statistics Report, there are 30.3 million people in the United States with diabetes. That’s close to 1 in 10 people. Among all these people living with diabetes, 90 to 95 percent have type 2 diabetes.. The percentage of people with diabetes increases with age. Less than 10 percent
of the general population has diabetes, but among those 65 and older, the incidence rate reaches a high of 25.2 percent. Only about 0.18 percent of children under the age of 18 had diabetes in 2015. Men and women get diabetes at roughly the same rate, but incidence rates are higher among certain races and ethnicities. American Indians and Alaskan Natives have the highest prevalence of diabetes among both men and women. The black and Hispanic populations have higher rates of diabetes than non-Hispanic whites.
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