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Thursday, December 19, 2019 4:28:54 PM
https://www.xxiicentury.com/published-clinical-studies/
17. Phase I – 26 Subjects
Response to varying the nicotine content of cigarettes in vulnerable populations: an initial experimental examination of acute effects
University of Vermont Center on Tobacco Regulatory Science
Higgins et al. – October 2016, Psychopharmacology. DOI: 10.1007/s00213-016-4438-z
There was no evidence of compensatory smoking with VLNC cigarettes in these vulnerable populations and there were significant reductions in nicotine withdrawal and cravings with VLNC cigarettes
These initial results in more vulnerable populations of smokers are encouraging regarding the feasibility of a national policy to reduce the nicotine content of cigarettes to very low levels without substantial adverse effects
Funded by a Tobacco Centers of Regulatory Science (TCORS) award (P50DA036114) from the National Institute on Drug Abuse and Food and Drug Administration
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