I was wondering if pruritis was a class effect, but in reading the transcript they mention that the follow on seems to have less plasma and skin exposure while preferentially hitting liver and intestine.
I agree w you on allocation of resources but to put in persepctive the 2b program is 340 patients. assuming about 100K per pt enrolled it's 34M. Not that huge a deal given their resources. If the PBC trial data looks poor then they hopefully will shelve the drug altogether
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