Dyadic International Inc (DYAI)

[dennisczy]

Yes you are right ronpopeil. Let me just paste what I wrote on microcapclub over here.

A problem of the mammalian systems such as CHO cell lines and the baby hamster kidney is their doubling time. It takes E. coli around 20 mins for cleavage but the mammalian cell takes around 20 to 30 hours to replicate itself.

This is where C1 has a clear advantage, and if after glycosylation,  glycan structures such as G0 is achieved, honestly C1 would likely be worth several times more than the current valuation just based on its speed. As microbial systems (which is what C1 is classified under) are not known to be able to glycosylate in a way that is comparable to the human sugar pattern (other than yeast after Glycofi glycoengineered it). Another advantage C1 has is its genomic stability. It is widely known that CHO cells are not very genomically stable (which means that it is more likely to mutate).

If I am not mistaken, Transgenic system (which as genetically modified plants and animals) was a more likely candidate to replace mammalian system due to their high productivity and ability to glycosylate in a way similar to humans, but they are not as well developed as microbial or mammalian systems.