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Wednesday, 11/13/2019 12:47:23 PM

Wednesday, November 13, 2019 12:47:23 PM

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ASRT~~Statement of Ownership (sc 13g)
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SECURITIES AND EXCHANGE COMMISSION



Washington, D.C. 20549



SCHEDULE 13G





Under the Securities Exchange Act of 1934





Assertio Therapeutics, Inc.

(Name of Issuer)





Common Stock, $0.0001 par value

(Title of Class of Securities)





04545L107

(CUSIP Number)





November 1, 2019

(Date of Event Which Requires Filing of this Statement)



Check the following box to designate the rule pursuant to which the Schedule is filed:



¨ Rule 13d-1(b)
x Rule 13d-1(c)
¨ Rule 13d-1(d)


*The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.



The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).










CUSIP No. 04545L107



1.
Names of Reporting Persons

I.R.S. Identification Nos. of above persons (entities only)

D. E. Shaw & Co., L.P.

13-3695715



2. Check the Appropriate Box if a Member of a Group (See Instructions)
(a) [ ]

(b)



[ ]
3.
SEC Use Only



4.
Citizenship or Place of Organization

Delaware



Number of

Shares

Beneficially

Owned by

Each

Reporting

Person With

5.
Sole Voting Power





-0-

6.
Shared Voting Power

3,986,178



7.
Sole Dispositive Power

-0-



8.
Shared Dispositive Power

4,059,416



9.
Aggregate Amount Beneficially Owned by Each Reporting Person

4,059,416



10.
Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ]



11.
Percent of Class Represented by Amount in Row (9)

5.0%



12.
Type of Reporting Person (See Instructions)

IA, PN









CUSIP No. 04545L107



1.
Names of Reporting Persons

I.R.S. Identification Nos. of above persons (entities only)

David E. Shaw



2. Check the Appropriate Box if a Member of a Group (See Instructions)
(a) [ ]

(b)



[ ]
3.
SEC Use Only



4.
Citizenship or Place of Organization

United States



Number of

Shares

Beneficially

Owned by

Each

Reporting

Person With

5.
Sole Voting Power





-0-

6.
Shared Voting Power

3,986,178



7.
Sole Dispositive Power

-0-



8.
Shared Dispositive Power

4,059,416



9.
Aggregate Amount Beneficially Owned by Each Reporting Person

4,059,416



10.
Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) [ ]



11.
Percent of Class Represented by Amount in Row (9)

5.0%



12.
Type of Reporting Person (See Instructions)

IN













Item 1.
(a) Name of Issuer
Assertio Therapeutics, Inc.

(b) Address of Issuer's Principal Executive Offices

100 South Saunders Road, Suite 300

Lake Forest, IL 60045


Item 2.
(a) Name of Person Filing

D. E. Shaw & Co., L.P.

David E. Shaw


(b) Address of Principal Business Office or, if none, Residence

The business address for each reporting person is:

1166 Avenue of the Americas, 9th Floor

New York, NY 10036


(c) Citizenship

D. E. Shaw & Co., L.P. is a limited partnership organized under the laws of the state of Delaware.

David E. Shaw is a citizen of the United States of America.


(d) Title of Class of Securities
Common Stock, $0.0001 par value

(e) CUSIP Number
04545L107

Item 3.
If this statement is filed pursuant to Rule 13d-1(b) or 13d-2(b) or (c), check whether the person filing is a:



Not Applicable



Item 4.
Ownership



As of November 1, 2019:



(a) Amount beneficially owned:



D. E. Shaw & Co., L.P.:





4,059,416 shares

This is composed of (i) 1,912,174 shares in the name of D. E. Shaw Valence Portfolios, L.L.C., (ii) 383,943 shares in the name of D. E. Shaw Oculus Portfolios, L.L.C., (iii) 3,944 shares in the name of D. E. Shaw Asymptote Portfolios, L.L.C., and (iv) 1,759,355 shares under the management of D. E. Shaw Investment Management, L.L.C.




David E. Shaw:



4,059,416 shares

This is composed of (i) 1,912,174 shares in the name of D. E. Shaw Valence Portfolios, L.L.C., (ii) 383,943 shares in the name of D. E. Shaw Oculus Portfolios, L.L.C., (iii) 3,944 shares in the name of D. E. Shaw Asymptote Portfolios, L.L.C., and (iv) 1,759,355 shares under the management of D. E. Shaw Investment Management, L.L.C.



(b) Percent of class:
D. E. Shaw & Co., L.P.: 5.0%
David E. Shaw: 5.0%






(c) Number of shares to which the person has:
(i) Sole power to vote or to direct the vote:
D. E. Shaw & Co., L.P.: -0- shares
David E. Shaw: -0- shares


(ii) Shared power to vote or to direct the vote:
D. E. Shaw & Co., L.P.: 3,986,178 shares
David E. Shaw: 3,986,178 shares


(iii) Sole power to dispose or to direct the disposition of:
D. E. Shaw & Co., L.P.: -0- shares
David E. Shaw: -0- shares


(iv) Shared power to dispose or to direct the disposition of:
D. E. Shaw & Co., L.P.: 4,059,416 shares
David E. Shaw: 4,059,416 shares


David E. Shaw does not own any shares directly. By virtue of David E. Shaw’s position as President and sole shareholder of D. E. Shaw & Co., Inc., which is the general partner of D. E. Shaw & Co., L.P., which in turn is the investment adviser of D. E. Shaw Valence Portfolios, L.L.C. and D. E. Shaw Oculus Portfolios, L.L.C. and the managing member of D. E. Shaw Investment Management, L.L.C. and D. E. Shaw Adviser, L.L.C., which in turn is the investment adviser of D. E. Shaw Asymptote Portfolios, L.L.C., and by virtue of David E. Shaw’s position as President and sole shareholder of D. E. Shaw & Co. II, Inc., which is the managing member of D. E. Shaw & Co., L.L.C., which in turn is the manager of D. E. Shaw Valence Portfolios, L.L.C. and D. E. Shaw Oculus Portfolios, L.L.C. and the managing member of D. E. Shaw Manager, L.L.C., which in turn is the manager of D. E. Shaw Asymptote Portfolios, L.L.C., David E. Shaw may be deemed to have the shared power to vote or direct the vote of 3,986,178 shares, and the shared power to dispose or direct the disposition of 4,059,416 shares, the 4,059,416 shares as described above constituting 5.0% of the outstanding shares and, therefore, David E. Shaw may be deemed to be the beneficial owner of such shares. David E. Shaw disclaims beneficial ownership of such 4,059,416 shares.



Item 5. Ownership of Five Percent or Less of a Class
Not Applicable



Item 6. Ownership of More than Five Percent on Behalf of Another Person.
Not Applicable



Item 7. Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person.
Not Applicable



Item 8. Identification and Classification of Members of the Group
Not Applicable



Item 9. Notice of Dissolution of Group
Not Applicable



Item 10. Certification
By signing below, each of D. E. Shaw & Co., L.P. and David E. Shaw certify that, to the best of such reporting person’s knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having such purposes or effect.









SIGNATURE



After reasonable inquiry and to the best of their knowledge and belief, the undersigned certify that the information set forth in this statement is true, complete and correct. A Power of Attorney, dated March 1, 2017, granted by David E. Shaw in favor of Nathan Thomas, is attached hereto.



Dated: November 12, 2019






D. E. Shaw & Co., L.P.


By: /s/ Nathan Thomas
Nathan Thomas

Chief Compliance Officer






David E. Shaw


By: /s/ Nathan Thomas
Nathan Thomas

Attorney-in-Fact for David E. Shaw

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