Friday, November 08, 2019 2:00:28 PM
That has NOTHING to do with Bavi.
CDMO doesn't own phosphatidylserine and it doesn't own receptors that might interact with PS as part of its mechanism of function. I explained several times why PS is a VERY POOR target for oncology as it is found in massive numbers when exposed including a tremendous sink of exposed PS on apoptotic cells that will titrate aways anti-PS antibodies. That is likely why Bavi has never succeeded in a controlled trial and why Bavi was given away for a song to a startup Chinese company. Cellular receptors that may interact with PS on cancer cells are found in orders of magnitudes lower levels than PS so represents far more prosing targets.
It gets tiresome having to repeat this.
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