RespireRx Pharmaceuticals Inc (RSPI)

[gfp927z]

Neuro, So Servier halted the MCI Phase 2? Did you hear what the toxicity issues were, seizure related or nausea/headache type? I guess I'm not that surprised, but it's still sad to see another AMPA upmodulator bomb out in Phase 2 (to go along with Lilly's LY-451395). Thanks for the info.

BTW, my idea that Organon might not be happy with Org-24448 and thus be bringing up Org-26576 as a replacement was meant to be just one of numerous possible reasons. My point was that since we don't know what the true reason is, we shouldn't assume that the reason is necessarily benign.

Concerning the FDA extending their investigation to Org-24448, if that happens it shouldn't be a surprise to anyone. It's an obvious risk we have going forward, and I'm figuring it as a likely event. If Org-24448 is clean and everyone knows it, that would help remove a lot of the uncertainty we're currently under.