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Re: antihama post# 2676

Friday, 10/18/2019 8:31:26 AM

Friday, October 18, 2019 8:31:26 AM

Post# of 3283
While a TDM-1 Pozi Combo trial bodes well for a HER2 exon 20 mutation trial, I need to walk back what I said regarding the same for EGFR exon 20 mutations since TDM-1 affects HER2 and I don't have any data showing it affects EGFR. However, the idea of doing a pozi P3 combo trial for EGFR exon 20 mutations is valid, I'm sure there's strong candidates for the EGFR pozi combo trial, Cetuximab (post 2546) comes to mind.