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mcbio

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mcbio

Re: DewDiligence post# 226428

Thursday, 10/17/2019 1:06:56 PM

Thursday, October 17, 2019 1:06:56 PM

Post# of 251540
ASMB - ASBM +29% on HBV presentations for AASLD

Am I reading it wrong or is the decline in HBsAg (along with other biomarkers) still relatively small for the combo? PR says: "...observed mean log changes of ≥0.6 for HBeAg (11 patients ≥0.5, 4 patients ≥1.0), >0.8 log for HBcrAg (7 patients ≥1.0, 3 patients ≥2.0) and ≥0.4 log for HBsAg (7 patients ≥0.5, 3 patients ≥1.0)."

How strong is the evidence that the combo will ultimately lead to a functional cure?
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