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Post# of 252218
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Re: ghmm post# 226089

Wednesday, 09/04/2019 6:48:57 PM

Wednesday, September 04, 2019 6:48:57 PM

Post# of 252218
ghmm. Yes according to my wife it’s a very buyable argument .
Dialysis patients on phosphate binders ( most are ) complain of constipation ... often only 2-3 bowel movements per week .
When they add Tenapanor bowel movements may increase to 5-6 times a week .
In my wife’s opinion most of her patients would consider this a good thing because it made them feel more “ normal “

The issue will be in the final P3 which is a mono therapy . There won’t be a binder to offset the “ loose stool “ ... so discontinue rate might be higher .

In end wife thinks it will be a blend of the 2 ... allowing patients to reduce the binders they are on when they add Tenapanor .... but not to the extent of causing diarrhea

I posted more on the other board
Kiwi

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