Innovation Pharmaceuticals Inc (IPIX)

[georgejjl]

Why Amgen's $13.4 Billion Otezla Buy Is A Boon For These Biotechs

https://www.investors.com/news/technology/amgen-stock-dips-deal-buy-celgene-drug-otezla/

How Otezla works
Though many people assume that plaque psoriasis is just a skin disease, it actually starts inside the body—so it’s important to keep that in mind.

Plaque psoriasis is associated with overactive inflammation in the body. Lab research has shown that an enzyme called phosphodiesterase 4 (PDE4), located inside cells, contributes to this inflammation.

“Otezla works from the inside to help reduce inflammation.”
-Dr. Erin Boh, board certified dermatologist

Otezla is called a PDE4 inhibitor—meaning it works inside inflammatory cells to reduce PDE4 activity. A reduction in PDE4 activity is thought to help reduce the overactive inflammation that happens in people with plaque psoriasis

https://www.otezla.com/plaque-psoriasis-treatment/mechanism-of-action

A key aspect of Brilacidin's mechanism of action, inhibiting Phosphodiesterase 4 (PDE4), may further support its use in treating Asthma, Psoriasis, Psoriatic Arthritis and Chronic Obstructive Pulmonary Disease (COPD), alongside other chronic autoimmune conditions.

http://www.ipharminc.com/brilacidin-1

Brilacidin is being developed as a novel, non-corticosteroid, non-biologic treatment, with formulation plans including oral tablets

http://www.ipharminc.com/press-release/2019/6/6/innovation-pharmaceuticals-signs-agreement-for-advanced-oral-tablet-technology-in-treating-inflammatory-bowel-disease?rq=tablet

So, a key aspect of Brilacidin's mechanism of action, inhibiting Phosphodiesterase 4 (PDE4), may further support its use in treating Asthma, Psoriasis, Psoriatic Arthritis and Chronic Obstructive Pulmonary Disease (COPD), alongside other chronic autoimmune conditions and it is being developed as an oral tablet.

IF Brilacidin works as good if not better than Otezla, then how much will Brilacidin be worth as a treatment for psoriasis, psoriatic arthritis and Crohn's disease and IBD, etc???

Good luck and GOD bless,