INmune Bio Inc. (INMB)
Alert Price: $8.82
12-Month Consensus Price Target: $13.00 (Maxim Group)
Website | Recent News
July was one of our most profitable months of 2019.
We delivered 6 solid winners in a row for a grand total of +270% in realistic gains!
We now plan to kickoff the month of August with what could be one of our biggest long-term winners yet.
Just like two of our most recent winners, the Company trades on the NASDAQ exchange and has tremendous growth potential.
Please turn your immediate attention to INmune Bio Inc. (INMB).
INMB is a clinical stage biotechnology company that is developing new immunotherapies that reprogram a patient’s innate immune system to allow the immune system to fight cancer and Alzheimer’s.
INmune Bio Inc. is a developing novel therapies targeting distinct parts of a patient’s innate immune system to fight disease. Drug candidates, INKmune™ and INB03, may be used to treat cancer. XPro1595 targets neuroinflammation as a cause of Alzheimer’s disease. INmune Bio’s product platforms utilize a precision therapy approach, promoting the body’s innate immune response to treat unsolved problems in medicine.
INMB's therapies provide treatment for diseases that effect millions of patients each year.
Alzheimer’s Disease – The Alzheimer’s disease therapeutics market will grow to be worth more than $12 billion annually by 2026.
Cancer Residual Disease – About 1.7 million patients are affected by this every year, with nearly 610,000 patients dying as a result.
Checkpoint Inhibitor Market – The global checkpoint inhibitor market will grow to be worth more than $40 billion annually by the year 2026.
About INmune Bio, Inc.
INmune Bio, Inc. is a publicly traded (NASDAQ: INMB) clinical-stage biotechnology company developing therapies targeting the innate immune system to fight disease. INmune Bio is developing three product platforms: two products that reengineer the patient’s innate immune system’s response to cancer and one product to treat neuroinflammation that is currently focused on Alzheimer’s disease. INKmune is a natural killer ( NK ) cell therapeutic that primes the patient’s NK cells to attack minimal residual disease, the remaining cancer cells that are difficult to detect, which often cause relapse. INB03 inhibits myeloid-derived suppressor cells (MDSC), which often cause resistance to immunotherapy, such as anti-PD-1 checkpoint inhibitors. XPro1595 targets neuroinflammation, which causes microglial activation and neuronal cell death. INmune Bio’s product platforms utilize a precision medicine approach for the treatment of a wide variety of hematologic malignancies, solid tumors and chronic inflammation. To learn more, please visit http://www.inmunebio.com.
INKmune-Cancer - in oncology patients that relapse, cells that are known to target residual cancer cells, fail to eliminate the remainder of the disease after treatment. INMB is working to keep this from happening with INKmune.
INB03-Alzheimers - targets myeloid derived suppressor cells, or MDSC, believed to be the reason that many cancer patients do not respond to checkpoint inhibitor treatments.
XPro1595-Cancer – is under development as a potential option for patients with Alzheimer’s disease, believed to be caused by neuroinflammation of brain cells. The company believes XPro1595 will inhibit neuroinflammation and the resultant cell death.
INMB's Pipeline's Multi-Billion Dollar Market Opportunity
• XPro1595 - Alzheimer’s/dementia market*
– 5.8 M patients in US
– 2019 est cost to care for US AD patients $280B
- Cancer residual disease market **
– 1,735,350 new cases and 609,640 people will die
– Initial targets: Ovarian Cancer and High Risk MDS
- Resistance to Checkpoint Inhibitors market***
– CPI’s work 27% of patients. CPI 2025 est market size $56B
– INB03 in combination with CPI’s should increase the number of patients sensitive to CPIs. – Initial targets: Melanoma and Renal Cell Cancer
All three of the candidates in the company’s pipeline are either currently in Phase 1 clinical studies or are about to begin Phase 1 clinical studies in the near term.
INB03 Australia Solid Tumors Initial Phase 1 Data Readout- Q3 ’19
INKmune UK Ovarian Cancer Initiate Enrollment of Phase 1/2 study - Q4 ’19
INB03 Australia Solid Tumors Initiate Combination Study, Additional Cohorts to Phase 1 Study- 1H ’20
XPro1595 UK Alzheimer’s Initiate Enrollment of Phase 1 Study - Q3’19
INKmune UK Ovarian Cancer Report Initial Phase 1 Data - 1H ’20
XPro1595 UK Alzheimer’s Early Data - Q1’20
INKmune UK Ovarian Cancer Initiate Phase 2 Study - 2H ’20
INB03 Australia/US Solid Tumors Initiate INB03 + CPI* Phase 2 Combination Study - 1H ’20
The Alzheimer Association believes in IMNB
In order to advance XPro1595 in the treatment of AD, INmune was recently awarded a $1 million grant from the Alzheimer’s Association.
The grant will support a biomarker-directed Phase 1 clinical trial in 18 patients with mild-to-moderate AD. XPro1595 will be administered subcutaneously once a week for three months and biomarkers of inflammation will be assessed at 0, 6, and 12 weeks.
This ringing endorsement from the Alzheimer Association should have potential investors sold on IMNB's potential to help treat this dreaded disease that effects 5.8M patients in the U.S. alone.
The Smart Money Is Buying Up Shares In IMNB
Insiders own 63% of the outstanding shares of INMB.
Insiders have spent $770,000 buying up company shares in the past two months.
The Company has zero debt!
The fact that insiders own 63% of the shares, has us bullish on INMB's growth potential.
Who would know better if the Company was undervalued than those working within.
Tiny Float = Big Move Potential
The public float for IMNB is just 2.98M
A float that low is a rarity for companies listed on the NASDAQ.
It also means the IMNB could moonshot if it were to see an increase in daily volume .
In fact, the first time IMNB broke over 100K in daily volume , its shares had their biggest single day move, climbing from $8.80 to $10.68, for a single day gain of over +21%!
INMB Trades Under $9 And Has A $13 Price Target
In March, Maxim Group launched coverage of INMB with a “buy” rating and $13 price target.
Analyst Jason McCarthy stated that INB03, a selective TNF inhibitor downregulates the immunosuppressive factors found in the tumor microenvironment, turning cold tumors hot. An open-label Phase 1 study is ongoing, with data expected in the second quarter of 2019.
He said XPro1595 selectively targets the soluble form of TNF and may inhibit activated microglia, a type of innate immune cell, representing a differentiated approach, compared with targeting beta amyloid or tau.
XPro1595’s preclinical data has been positive, he said, and a Phase 1 study is scheduled to start in the second quarter of 2019. Also initiating in the second quarter of 2019 is a Phase 1/2 study of INKmune, a modified tumor cell line that primes existing natural killer cells.
“Innate immunity is a space that continues to evolve and rise behind CAR-T and checkpoints (both target adaptive immunity), with multiple players in the space, including big pharma/biotech,” Mr. McCarthy said. “INmune's programs should report data in 2019 providing catalysts for the stock to support a higher valuation,” he added.
With an upside of over +47%, now could be the perfect time to start building a position in INMB.
INmune Bio Co-Founder and CEO RJ Tesi Presents at Cambridge Healthcare Institute’s 7th Annual Immuno-Oncology Summit
This week, RJ Tesi, M.D., co-founder and CEO , will present at the Cambridge Healthcare Institute’s 7th Annual Immuno-Oncology Summit.
We will be keeping a close eye on this, as any data that comes out could serve as a strong bullish catalyst for INMB's share price.
We've done our very own chart analysis on INMB, and we the potential for a move of over 21%!
The stock has seen multiple bounces and reversals from these levels, which leads us to believe that now may be the perfect entry point for those looking to capitalize on INMB's next potential chart reversal.
We don't think INMB will be trading under the radar for much longer.
Any positive data released by the Company could grab the attention of Wall St .
With its low-float, INMB could see a huge run-up.
ZERO Debt and Heavy Insider Ownership have us bullish heading into the 2nd half of 2019.
(*Remember to use a Stop-Loss Order or basic Limit Order to protect your gains, as well as limit possible losses.)
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Recent INMB News
- Current Report Filing (8-k) • Edgar (US Regulatory) • 03/15/2023 08:04:01 PM
- Current Report Filing (8-k) • Edgar (US Regulatory) • 03/03/2023 09:48:34 PM
- INmune Bio, Inc. Announces 2022 Results and Provides Business Update • GlobeNewswire Inc. • 03/02/2023 09:05:52 PM
- Current Report Filing (8-k) • Edgar (US Regulatory) • 02/22/2023 09:01:19 PM
- Current Report Filing (8-k) • Edgar (US Regulatory) • 02/22/2023 09:01:14 PM
- Statement of Changes in Beneficial Ownership (4) • Edgar (US Regulatory) • 02/21/2023 09:10:30 PM
- Statement of Changes in Beneficial Ownership (4) • Edgar (US Regulatory) • 02/21/2023 09:08:00 PM
- Statement of Changes in Beneficial Ownership (4) • Edgar (US Regulatory) • 02/21/2023 09:07:10 PM
- Statement of Changes in Beneficial Ownership (4) • Edgar (US Regulatory) • 02/21/2023 09:05:33 PM
- Statement of Changes in Beneficial Ownership (4) • Edgar (US Regulatory) • 02/21/2023 09:04:23 PM
- Statement of Changes in Beneficial Ownership (4) • Edgar (US Regulatory) • 02/21/2023 09:03:19 PM
- INmune Bio, Inc. to Report Fourth Quarter and Full-Year 2022 Results and Provide a Corporate Update on Thursday, March 2 • GlobeNewswire Inc. • 02/21/2023 02:00:00 PM
- Current Report Filing (8-k) • Edgar (US Regulatory) • 02/10/2023 11:11:19 AM
- INmune Bio, Inc. Receives Approximately $6.4 Million in Research and Development Rebates from Australia and the United Kingdom • GlobeNewswire Inc. • 02/08/2023 01:45:00 PM
- Current Report Filing (8-k) • Edgar (US Regulatory) • 01/25/2023 02:08:03 PM
- INmune Bio, Inc. Announces Pre-Clinical Data That Support a Pioneering Approach to Treating Duchenne Muscular Dystrophy • GlobeNewswire Inc. • 01/25/2023 12:45:00 PM
- Current Report Filing (8-k) • Edgar (US Regulatory) • 12/22/2022 09:01:20 PM
- INmune Bio, Inc., Virginia Commonwealth University, and Barrow Neurological Institute Receive Department of Defense Funding to Study the Role of Traumatic Brain Injury in the Development of Alzheimer’s Disease • GlobeNewswire Inc. • 12/22/2022 01:00:00 PM
- Current Report Filing (8-k) • Edgar (US Regulatory) • 12/12/2022 10:04:48 PM
- Current Report Filing (8-k) • Edgar (US Regulatory) • 12/09/2022 09:01:51 PM
- Maxim Group Keeps Their Buy Rating on Inmune Bio (INMB) • TipRanks • 12/09/2022 06:55:06 PM
- INmune Bio, Inc. Data at ASH Highlight Innovative Natural Killer Cell Therapeutic Platform Showing 100+ Day Persistence of Cancer Killing Memory Like NK Cells in Patients with AML/MDS Following Treatment with INKmune™ • GlobeNewswire Inc. • 12/08/2022 01:00:00 PM
- Current Report Filing (8-k) • Edgar (US Regulatory) • 12/07/2022 09:02:30 PM
- INmune Bio, Inc. Reports Combination Therapy with INB03™ Overcomes Resistance to Trastuzumab-Deruxtecan in MUC4 expressing HER2+ Breast Cancer • GlobeNewswire Inc. • 12/06/2022 09:00:00 PM
- INmune Bio, Inc. Focused on Novel Clinical Trial Designs to Advance Next Generation of Alzheimer’s Disease Treatments • GlobeNewswire Inc. • 11/29/2022 01:00:00 PM
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