Innovation Pharmaceuticals Inc (IPIX)

[MinnieM]

I haven't been able to sit and read the full article, but, the company states it.
http://www.ipharminc.com/press-release/2017/12/27/innovation-pharmaceuticals-obtains-direct-evidence-of-molecular-pathways-modulation-in-tumors-from-first-patients-in-kevetrin-ph2a-ovarian-cancer-trial?rq=modulate%20p53

Modulation of the p53 protein was observed in response to administration of Kevetrin.

Article you were referring to.
https://journals.lww.com/hemasphere/Pages/articleviewer.aspx?year=2019&issue=06001&article=01570&type=Fulltext

Summary/Conclusion:
Our results show kevetrin alters several key genes and cellular metabolism. Along with cellular data, this study could provide a rationale for an experimental trial in AML patients, especially those carrying TP53 mutation who actually have very few therapeutic options.

In Reply to 'Barron4664' regarding question in bold.
Hope your right. However, havent read the paper yet. Only seen the abstract. To say its a fact is premature. Does the paper say kevetrin does? Or does it say it has the potential to modulate? Let us not forget all the glowing papers published on Nutlins and P53. Hasn’t helped Merck. However at least with IPIX the safety profiles are much better than Merck’s products. So you may be right. Just can’t say it means all that much yet until the human trial data is in. Thats all. I hear you mang, just checking my years long confirmation bias.