Perhaps they should not have strayed from the ph 2a dosages which resulted, in part, to these words included in a pr by management(management increased 2b dosages after results stated).
Investigator Comments
Cellceutix would also like to share some observations and comments from Principle Investigators (PIs) overseeing different participating clinical sites in the trial. Numerous PIs noted patients expressed a desire to have access to Prurisol following the study's conclusion. Moreover, the Company learned that some patients were previously unsuccessfully treated with other therapies, including biologics and apremilast (Otezla®).
Included below is a sampling of responses that were authorized to be published:
"Well designed study, patients were pleased, minimal to no side effects."
"Good tolerability was shown with very few AEs reported. Good compliance and good patient satisfaction."
"Overall impression of the study is very positive, as well as the patients' satisfaction."
When asked, "Why would you choose Prurisol (should it be approved) over another oral compound for psoriasis?" and "Why would you choose Prurisol over an injectable biologic?" responses included:
"Because [Prurisol] does not cause any severe side effects. Patients dislike needles and injections because they cause pain and discomfort."
"Patients overall prefer oral medications over injectable medication. Our experience with injectable studies for other indications has been that many subjects do not like taking them and those studies tend to be difficult compared to oral medications to recruit subjects."
"Because of [Prurisol's] low side effect profile."
"Patients prefer oral treatments
Switching from spectacular B IBD enema treatments to untested pill form mid stream. Pill in discovery/ next phase on hold.
Switching from spectacular preventative swish and spit B to pill (encapsulated B) form for severe oral mucositis midstream. Pill in discovery/ next on hold.
Paying for an office large enough to house 50-75 employees, maybe more,when they could relocate the 3 to 5 to 7 people still there, into a different office at the same location.
If at ain't broke, don't fix it. Waste not, want not. Time is money.
