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Sunday, May 19, 2019 2:01:12 PM
A couple of references to the discussion that started in February with Sleuth speculation about a possible relationship to DuPont
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=146624105
and
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=147238200&txt2find=dupont
Could CBD Oil work better with Omega 3?
We know that CBD oil effects cell metabolism through the endocannabinoid system. And we know this system is involved in a wide range of physiological functions, including the regulation of our mood, inflammation response, immune system, and metabolism.
We know that CBD mimicks the body’s endocannabinoids - they “unlock” the receptors CB1 and CB2, creating a variety of effects.
Now how are Omega-3s connected to the Endocannabinoid System?
Endocannabinoids are lipids made from the cells’ omega-3 and omega-6 content. Once cells build up a sufficient inventory of these fatty acids, endocannabinoids are created rapidly and as-needed in response to brain activity and stimuli (like stress and exercise).
Omega-3s are directly involved in the synthesis of endocannabinoids, and also react with existing endocannabinoids to create omega-3-derived endocannabinoid epoxides (which have powerful anti-inflammatory properties). Due to the important role that omega-3s have in the cell membrane, researchers believe that omega-3s also serve as crucial anchors for endocannabinoid cell membrane receptors.
To put it simply, omega-3s and endocannabinoids are totally dependent on each other in a healthy brain and body. And this connection explains why the anxiety and pain relieving effects from taking CBD oil are similar to the results achieved from receiving adequate omega-3 supplementation over time.
As a side note, Omega- 3 deficiency is a widespread problem impacting some 95% of adults in the United States. Research as shown that his deficiency has serious consequences for the healthy functioning of our endocannabinoid systems.
And omega 3-deficient diets don’t just limit the creation of beneficial endocannabinoids and the omega-3-derived endocannabinoid epoxides. Studies have also shown that omega-3-deficiency creates dysfunctional endocannabinoid receptors, uncoupling them from the protein and altering signaling pathways in the brain
Another side note: the overall ratio of Omega 3 of 6 to 3 in tissue is 11:1 in plasma 15:1 yet they recommend a ratio of 3:1??? True the western diet is like 20:1 but the truth is that omega 6 is mostly processed oils which is non functional. A healthy diet of omega 6 consists of nuts and seeds as well as meat eggs and cheese.
So there's deep involvement of omega 3s in the endocannabinoid system and when compared to most omega 3 supplements, CBD has clear advantages. The effects appear quickly, where omega 3s take longer to work – often many weeks of consistent consumption. These rapid effects probably explain why CBD has created such a buzz. With CBD products, people are also willing to take an adequate dose, but that often isn’t the case with omega 3 products.
CBD, however, does not solve the underlying omega-3 deficiency problem.
Most physiologists and biologists know that single molecules are rarely a cure-all for complex health issues. Unfortunately, this point often gets missed when we get too focused on isolated substances — either because of the pharmaceutical and health industry’s desire for patentable products or the appeal of easily understandable buzzwords. The human body and cell metabolism are extremely complex and dependent upon the interactions of a multitude of factors (e.g. genes, environment, nutrition, microbiome, age, gender, etc). Therefore, it’s highly unlikely that changing just one factor will solve chronic conditions for most people.
There isn’t a single substance – whether that’s CBD or even omega 3s that will ever give us a one-way ticket to good health. But when we understand the underlying mechanisms of the body and employ a synergy of wholesome efforts, we’ll be able to carve a better path forward.
That being said, until CV Sciences comes out with their new Omega 3 Pro+CBD Oil product labeled on New Harvest, start combining your Omega 3 with your CBD oil.
My next post will explore the synergistic effects of taking CBD with Omega 3, Melatonin and D3. Now that combination provides a synergy of beneficial effects.
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