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Re: Rdunn88 post# 262502

Thursday, 05/09/2019 3:56:06 AM

Thursday, May 09, 2019 3:56:06 AM

Post# of 403036
How many million dollars does it cost to do a trial for 10 weeks on 100 people? I don’t think it’s $40 million I don’t even think it’s $10 millionOral M is an acute condition. It’s interruption by an effective drug can be quickly demonstrated in any individual patients. Drug trials can be measured in weeks not months or years or decades. Any treatment will be an orphan drug with all that special status. It is an unmet need in an indication that has severe consequences The phase 2 trial has already demonstrated statistical significance in efficacy given these factors it is my humble opinion based on my experience then we could expect a phase 3 trial in Europe of approximately 100 people or even a phase 2B Trail. This would be placebo controlled could go on very quickly and would not be that expensive and may be taken care of by a partner or perhaps by the family office. Or given our higher price perhaps we can go back to a less diluted trough. Hey placebo controlled phase 2B given the urgency would probably allow accelerated approval in Europe. That would bring in some revenue could pay for trails in the US or maybe the FDA could just look at the European phase for data. One could look at the other board and many of us share through Patrick Cox in the Alzheimer’s base to see how this is done
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