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Re: janeyH post# 2184

Monday, 04/29/2019 11:44:50 PM

Monday, April 29, 2019 11:44:50 PM

Post# of 2495
Upcoming Presentation

From CorMedix Website:

Presentation of Lock It 100 at the National Kidney Foundation in Boston May 10th 10:15am during their Late Breaking Research Presentation schedule.

Presenter looks to be a big deal.
Presenter: About Dr. Anil Agarwal, MD
Anil K Agarwal MD, FACP, FASN, FNKF, FASDIN
Professor of Medicine
Chief, Section of Nephrology at University Hospiital East
Director, Interventional Nephrology
Director of Clinical Scholarship for FAME
The Ohio State University Wexner Medical Center

Late-Breaking Research Presentations: The AWARD Trial and The LOCK-IT-100 Study Results
Friday, May 10, 2019 10:15 AM - 11:15 AM Room 312, Hynes Convention Center
Chair: Joseph Vassalotti, MD, FNKF
General CME/CE
Session Description
LOCK-IT-100: LOCK-IT-100, a multicenter, double-blind, active controlled trial randomized 805 hemodialysis (HD) patients using tunneled dialysis catheters at 70 US sites to compare Neutrolin® (an antimicrobial catheter lock solution containing taurolidine 1.35%, citrate 3.5%, & heparin 1000 U/mL) with heparin (1000 U/ml) for efficacy and safety in reducing catheter-related blood stream infections (CRBSIs) in HD patients. The trial was terminated early for efficacy by the Data Safety Monitoring Board, based on a 72% reduction in the risk of CRBSI by Neutrolin® compared to heparin, with no safety concerns identified. The LOCK-IT-100 trial demonstrated reduced risk of CRBSIs, a major cause of preventable hospitalizations, antibiotic use, healthcare costs, and excess mortality in HD.

Objectives
Discuss the results of LOCK-IT-100, a landmark randomized, controlled trial of an investigational catheter lock solution containing taurolidine, which demonstrated a statistically significant reduction in catheter-related bloodstream infections (CRBSIs) in patients on hemodialysis.

Program Tracks
Physician Program
Advanced Practitioner Program
CME/CE Credits/Contact Hours: 1
Presentations
Exercise and Physical Function in Older Adults with Advanced CKD: The AWARD Randomized Controlled Trial

10:15 AM - 10:40 AM
Speakers: Daniel Weiner, MD, MS, FNKF;Stephen Seliger, MD, MS
LOCK-IT-100: An Investigational Antimicrobial Catheter Lock Solution Shown to Reduce Life Threatening Infections in Hemodialysis Patients
10:40 AM - 11:05 AM
Speaker: Anil Agarwal, MD, FNKF
Question & Answer
11:05 AM - 11:15 AM
Speakers: Stephen Seliger, MD, MS;Anil Agarwal, MD, FNKF
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