Biotech Values

[rfj1862]

I think there's a whole generation of researchers and scientists who've been convinced that Amyloid Beta is the root cause of AD.

Holding onto that belief is, in my opinion, inane.

While viral is the leading suspect, that doesn't make it the only cause. And it could turn out to be another wild goose chase. I doubt it, but I can't absolutely rule it out.

And if I were to become aware of early AD symptoms in myself, I would do everything in my power to find a doctor willing to give me successive courses of antivirals, antifungals, and antibacterials.

I don't think that viruses or a previously unknown prion are out of the question at all as causative agents in AD! Bacteria and fungi probably far less likely. I don't think that a lack of efficacy of IVIG in AD says anything because, of course, IVIG can't get past the blood-brain barrier.

As far as beta-amyloid production being the root cause of AD--I don't think that is out of the question either. There are other protein misfolding diseases that cause neurologic (and cardiac) symptoms--for example, transthyretin amyloidosis, which can have rapid and severe effects on the peripheral nervous system. The type that affects the peripheral nervous system is primarily hereditary, but the cardiac type (which also has neurologic effects) is mostly caused by misfolding of wild-type protein, although there are also some hereditary cases.

So since this is the biotech values board are there any worthwhile AD investments out there?