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Re: SmokerX post# 23112

Tuesday, 03/19/2019 7:00:21 PM

Tuesday, March 19, 2019 7:00:21 PM

Post# of 41257

Both of the present case studies involved septic discitis. Yet, it is interesting to note that the second study was due to a fungal infection (i.e., Candida albicans). While the effectiveness of Si3N4 against various fungal species is unknown, several recent reports suggest that its antimicrobial behavior may be the result of multivariate mechanisms. For example, contact with polished Si3N4 surfaces resulted in the lysis of a gram-negative phylum, Porphyromonas gingivalis during a six-days of in situ exposure. The reported mechanism included the conversion of ammonia (NH3) to peroxynitrite (ONOO-), a powerful oxidative agent, which was able to permeate the bacteria’s extracellular membranes. Once inside, it reduced lipid concentration, disrupted cellular functions, and damaged nucleic acids resulting in eventual death



https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832668/

the infected area of the leaves was reduced by ~95%.
The likely mechanism likely involves electrical
attraction to, and attachment of silicon nitride
particles to oppositely-charged pathogen spores."



So the way I`m reading this is the top quote represents the mechanism of how fungals die. The bottom quote suggests an attraction like magnets between a fungus and SiNi nano particles. So not only does it kill fungus it sticks to them like a magnet then a slow release antifungal(peroxynitrite) goes to work. This sounds hard to replicate using bulk peroxynitrate. You would have to develop the magnets then a way to slow release it.

I might be way off here.

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