PROTALIX BIOTHERAPEUTICS, INC. (PLX)

[Spideyboy]

I would feel that would make sense about institutionals getting in.

Next things to come out of this for news I'd expect to be, outcome of discussions with FDA on met/unmet requirements to be eligible for AA review, and perhaps some low 102 R&D milestone cash from Chiesi?

But also agreed that I'd expect things to trickle down to the 0.45 mark before any news actually comes out. Similar to what we saw just a few weeks ago with the SP increase pre-Balance PK data release, and then went back down again.

Tex- Yes the market doesn't take into account 106/110 at the moment, and I can see why that would be the case. Until cash/approval comes in, analysts will see this as a 40+ million dollar a year cash burn with no guarantee of any new approvals. If you look at that just at face value you can understand why you would need much savvier than your regular analyst/investor to take into account the science, potential and risk/reward for getting in now vs the more comfortable position after an approval, as there will still be much rewards to be gained as potential sales come in.

106 is at least one phase 3 clinical trial away, and 110 will be probably a bigger phase 2 and then a 3. So still a ways to go for a company with this cash burn. Essentially it's on 102 to bring the real noticeable value to the company. Based on the science, research, clinical data thus far and the deal value with Chiesi, my understanding leads me to strongly believe in 102's potential. But for many others it may appear too risky.