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Re: misiu143 post# 35981

Monday, 02/11/2019 9:48:24 PM

Monday, February 11, 2019 9:48:24 PM

Post# of 233130
Thank you, the misconceptions were strong here today, I wanted a detailed explanation for new investors trying to wade through the posts.

For the half life, I found this:

In a study of multiple subcutaneous (SC) doses of PRO-140 in adults with HIV, the mean terminal half-lives were 3.4 days (162 mg dose) and 3.7 days (324 mg dose).8 In a study of single intravenous (IV) doses of PRO-140 in adults with HIV, the mean terminal half-lives were 3.13 days (5 mg/kg dose) and 3.33 days (10 mg/kg dose).9



Since it went up from 3.4 days at 162mg (SC) to 3.7 days at 324mg. Doubling the dose again, I suspect at 700mg, the half-life will be at least 4 days.
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