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Re: runncoach post# 7919

Sunday, 01/27/2019 7:15:24 PM

Sunday, January 27, 2019 7:15:24 PM

Post# of 21541
Yes, I agree:

No. 5 — “Saving Brain Connections by Targeting Synaptic Proteins May Treat Alzheimer’s, Study Finds“

"Researchers at the Karolinska Institutet in Sweden reported how proteins in nerve cell synapses — the junctions between two nerve cells that allow them to communicate — are abnormal in the brains of patients with Alzheimer’s disease, correlating with the rate of cognitive decline. The findings support the therapeutic targeting of synaptic proteins as a potential strategy for early disease intervention."

This is the core thesis of Bryostatin. Synapses are lost in AD, and Bryostatin, through PKC-e pathway, restores synapses.

The Karolinska Institutet appears to still be doing preclinical work.



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