OTC•ROCKETS

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b]$INSY PIPELINE UPDATES

INSYS anticipates that it will have a number of critical interim steps and proof points across its diverse product portfolio over the next several months. This includes two potentially life-saving investigational products using its spray technology that are in advanced stages of clinical development: a) naloxone nasal spray for opioid overdose, and b) epinephrine nasal spray for anaphylaxis. It also includes clinical development efforts focused on cannabinoids: a) CBD oral solution as an investigational treatment for childhood absence epilepsy (Phase 2), b) infantile spasms (Phase 3), c) Prader-Willi Syndrome (Phase 2); and, d) dronabinol inhalation as a potential treatment for a variety of conditions, including anorexia in cancer. The following information updates important upcoming milestones for each of these innovative molecules and novel drug delivery systems.