Synaptogenix Inc (SNPX)

[runncoach]

Finally got a chance to skim through last week's different alzheimer's news headlines and several on the topic of the "blood brain barrier" really stick out IMO.

https://www.beingpatient.com/leaky-blood-vessels-alzheimers/

https://newatlas.com/alzheimers-blood-brain-barrier-early-sign-treatment/58056/

It certainly is intuitive that a leaky BBB would possibly allow for toxins and damage in the brain that could trigger plaques to form as a method of protection. The reason I say this is interesting is all the research done on BBB repair and protection conducted on PKCe modulators and specifically bryostatin. In fact when the brain takes a hit or some type of physical trauma, the body reflexively increases pkce levels. If indeed BBB breakdowns are a potential cause for alzheimer's, bryostatin's ability to promote BBB homeostatis would be the first place I would look. Take fwiw.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000781/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041549/

https://www.fasebj.org/doi/abs/10.1096/fasebj.30.1_supplement.706.7

In fact the NIH has been funding research into the TBI/blood brain barrier repair to the tune of around 300k+ per year.
http://grantome.com/grant/NIH/R01-NS099918-02