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Re: boston745 post# 21896

Saturday, 01/19/2019 4:29:59 AM

Saturday, January 19, 2019 4:29:59 AM

Post# of 40903

Titanium alloys are susceptible to hydrogen absorption which can induce precipitation of hydrides and cause embrittlement, leading to material failure.



Hmm, I wonder why they switched to a modular design utilizing a chrome cobalt head over a Titanium head, unlike the biomedtrix monoblock system in micro and nano hip implants. Why did the manufacturer want a stem that snapped in half back to "analyze"? Pretty obvious what the issue was if you ask me.

titanium's capacity for osseointegration



It does, however, sometimes bio-accumulate in tissues that contain silica.



These two quotes sound like a dichotomy to me. Replace Silica in bone and you get brittle bones. Where do you think the main area of bio accumulation may be? Let me throw a guess. The area of direct contact? the area we're seeing an affinity for osseointegration of titanium? I would warranty that osseo integration until I get my truck out of your drive way. I`m going to coin a new term for this: PSEUDO osseointegration unlike TRUE osseintegration. The difference being mostly defined by The body encapsulating the implant vs. fully assimilating it. This may be the reason why we're seeing revision surgery for titanium implants loosening ALL DAY SON. While SiNi seems to have a spotless track record.

However are we playing to win here of just get my truck out of your driveway and avoid a lawsuit? There's plenty of low hanging fruit involving metallosis and Biolox delta fracture to have to try and prove titanium fracture or loosening as inherent flaws by the manufacturers right now.

Titanium Dioxide in blood.


I think you`re barking up the wrong tree here, although:

literature that show smaller titanium dioxide particles are more likely to pose carcinogenic


and

Molecular research suggests that cell cytotoxicity due to TiO
2


However

titanium dioxide nanoparticles have low to negligible solubility


I think it's like 90% is easily eliminated as waste in the body. The rest can go to weakening bone structure or whatever. I dont think they care. You might get it labeled in California but I don't think it will gain recognition as a growing concern in the medical industry.

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Ok get ready bears I'm about to bad mouth this SINTX and give them my what for(guaranteed you didnt get this far and TLDR'd out of here long ago).

and is developing a new generation of orthopaedic bearings for hip and knee arthroplasty.



NO YOU ARE NOT. The implants are developed They`re sitting on Sonny's desk since the ice ages. This is some BS. Considering what we're seeing is a femoral head and what appears to be a titanium knee with SiNi coating this all seems to be well thought out. Why are we not seeing a SiNi knee or SiNi femoral stem? What else needs to be DEVELOPED before anything is actually launched? A Sini coated femoral stem? A SiNi coated femoral head? A SiNi doped HA coating?

Amedica/US Spine, a spine and reconstructive implant and instrument manufacturer focused on unique silicon nitride (SiN) technologies, implanted its first silicon nitride total hip implant this week in the international marketplace. A patient at the George Provincial Hospital in Western Cape South Africa received the implant that uses an Infinia silicon nitride ceramic femoral head as part of the total implant.



https://www.todaysmedicaldevelopments.com/article/medical-device-design-manufacturing-amedica-us-spine-reconstructive-market-022111/

Where is the CEO escorted out of the building? I cant find the link with him discussing launching hips in Europe within the next year from 2014. When we're discussing implanting the device in 2011 and it's now 2019 and we're discussing development?? This seems like reversion rather than progression. Is this intentional? We don't know since Sonny hasn't addressed this little tidbit and refuses to take questions for obvious reasons. Not suggesting the guy is engaging intentionally in sabotage. I dont think so. Is SINT hitting milestones? are they making progress that demonstrates due diligence? Is buying US spine and essentially running their products off the map acceptable performance as a company?

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