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Monday, January 14, 2019 8:05:56 AM
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(strategic elision of my thoughts about "AutoEich999")
As far as Pluristem (which is the reason I'm here!) I'm very excited about the coming months. The two recent presentations, where two physicians provided clinical evidence that different pathologies that cause terrible damage to the ability of blood vessels to perfuse tissues (Buerger's disease and Peripheral Arterial Diseases) can be dramatically reversed. What we have seen is patients in pain, watching their limbs develop gangrene, and facing imminent amputation and death, are brought back from the brink.
I do understand that two patients do not constitute a statistical sample, BUT, we have two top notch specialists, who believe that the reversal of the patient's devastating progression toward oblivion was halted by the intervention with Pluristem's PLX-PAD.
It's worth rereading Prof. Yoffe's statement (from recent article):
Following treatment with PLX-PAD cells, we observed demonstrable restoration of the patient’s peripheral blood supply to the injured limb, which was manifested by a significant improvement in color, warmth, wound size and reduced pain. One year following treatment, the wound is now fully closed, the patient was able to resume normal activities and amputation was prevented. This treatment highlights PLX-PAD’s ability to reduce inflammation, stimulate growth of new blood vessels and support treatment in ischemic conditions such as Buerger’s disease and Peripheral Arterial Diseases (PAD). Additionally, the other limb, which was in earlier stages of the disease, also showed signs of improvement demonstrating the cells’ ability to prevent progression of the disease and act as a potential systemic treatment. I am highly encouraged by these results providing hope for Buerger’s disease patients and am happy to see the significant improvement in the patient’s medical condition, quality of life and overall wellbeing.”
Dr. Lantis using PLX-PAD for a patient with CLI made similarly enthusiastic statements. These are serious, sober medical scientists, with huge clinical experience. They did not think the patient's healing was coincidence. We're accumulating solid evidence and it's been all positive so far. There's a lot here to be optimistic about!
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