Innovation Pharmaceuticals Inc (IPIX)

[Lemoncat]

It hasn't been disclosed yet. I assume we were the victim of sample size that was too small in the P2A 200mg arm along with overly aggressive subgroup analysis by IPIX.

This probably resulted in both of the phase 2B arms failing to do any better than placebo much like the 50mg, 100mg, and 150mg in the phase 2A. If the company saw anything resembling PASI75 > 20% they would have put a positive spin on things. It must have been completely hopeless for them to not even PR it and just scrub it from the pipeline.

The whole thing doesn't sit well with me. A number of conspiracy theories move through my head (CRO incompetence, sabotage, a Celgene partnership wanting it to disappear, etc.) The simplest answer though is that we were misled by the the 200mg arm in phase 2a and Prurisol was no better than Ziagen (or placebo) in treating psoriasis in a statistically powered trial.