InvestorsHub Logo
Followers 17
Posts 936
Boards Moderated 0
Alias Born 04/26/2010

Re: Lemoncat post# 253077

Tuesday, 01/01/2019 12:27:09 PM

Tuesday, January 01, 2019 12:27:09 PM

Post# of 403028
Yes, placebo rate in IPIX cisplatin Q1W group is a headscrather. Placebo rate in Q3W group was in line (sort of) with other trials:
placebo cisplatin Q3W
Brilacidin: 10 / 14 or 71.4 %
GC4419: 17 / 28 or 60.7 %
Dusquetide: 18 / 22 or 81.8 %

That brings up another anomaly between these three trials - placebo arm performance in general. Maybe risk ratios are the best way of pointing that out.
Risk Ratio (SOM incidence ratio) in placebo cisplatin groups, Q1W over Q3W.
Brilacidin: 0.64
GC4419: 1.11
Dusquetide: 0.76

Only Galera had worse performing cisplatin Q1W group. Granted, map of literature SOM rates resembles bird shot from shotgun on a barn wall. Still, I can't help but wonder the above ratios.

"I would rather have questions that can't be answered than answers that can't be questioned." Richard P. Feynman

Volume:
Day Range:
Bid:
Ask:
Last Trade Time:
Total Trades:
  • 1D
  • 1M
  • 3M
  • 6M
  • 1Y
  • 5Y
Recent IPIX News