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Tuesday, January 01, 2019 12:27:09 PM
placebo cisplatin Q3W
Brilacidin: 10 / 14 or 71.4 %
GC4419: 17 / 28 or 60.7 %
Dusquetide: 18 / 22 or 81.8 %
That brings up another anomaly between these three trials - placebo arm performance in general. Maybe risk ratios are the best way of pointing that out.
Risk Ratio (SOM incidence ratio) in placebo cisplatin groups, Q1W over Q3W.
Brilacidin: 0.64
GC4419: 1.11
Dusquetide: 0.76
Only Galera had worse performing cisplatin Q1W group. Granted, map of literature SOM rates resembles bird shot from shotgun on a barn wall. Still, I can't help but wonder the above ratios.
"I would rather have questions that can't be answered than answers that can't be questioned." Richard P. Feynman
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